potassium channel — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10674	Potassium Channel Activator 1	ZINC34634569	Potassium Channel
	Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood disorders ADHD, schizophrenia, and other psychotic states.		Potassium Channel
T0690	Quinine		Potassium Channel , Platelet aggregation , Parasite
	Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances...		Potassium Channel , Platelet aggregation , Parasite
T20968	CyPPA		Potassium Channel , Dopamine Receptor
	CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolarization.		Potassium Channel , Dopamine Receptor
T10977	DCEBIO		Potassium Channel
	DCEBIO stimulates the secretion of Cl- through the activation of the hIK1 K + channel and the activation of the apical Cl- conductance. DCEBIO is a derivative of 1-EBIO and a very strong activator of Cl- secretion by T84...		Potassium Channel
T27624	Iptakalim Hydrochloride		Potassium Channel , AChR
	Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Iptakalim is also a K(ir) 6.1/SUR2...		Potassium Channel , AChR
T15385	Glibornuride		Potassium Channel
	Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent.		Potassium Channel
T13164	Tipepidine hydrochloride		Potassium Channel , Dopamine Receptor
	Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect.		Potassium Channel , Dopamine Receptor
T2604	1-EBIO		Calcium Channel
	1-EBIO (1-EBIO) is a calium channel agonist.		Calcium Channel
T14982	Clofilium tosylate		Potassium Channel
	Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3.		Potassium Channel
T9714	Atpenin A5		Potassium Channel
	Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1].		Potassium Channel
T37709	2,2,2-Trichloroethanol		Potassium Channel , Endogenous Metabolite
	2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. 2,2,2-trichloroethanol activates a nonclassical ...		Potassium Channel , Endogenous Metabolite
T8189	Dihydroberberine		Potassium Channel , HSP , HER
	Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti...		Potassium Channel , HSP , HER
TN1092	O-Nornuciferine		Potassium Channel , HER
	O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.		Potassium Channel , HER
T10979	DCPIB		Potassium Channel , Chloride channel
	DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM, demonstrating at least 100-fold higher affinity over TREK1...		Potassium Channel , Chloride channel
T4294	NS 11021	NS11021	Potassium Channel
	NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels		Potassium Channel
T0386L	Ropivacaine	LEA-103 HCl	Potassium Channel , Sodium Channel
	Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.		Potassium Channel , Sodium Channel
T0386	Ropivacaine hydrochloride	Ropivacaine monohydrochloride	Potassium Channel , Sodium Channel
	Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity.		Potassium Channel , Sodium Channel
T13320L	VU591		Potassium Channel
	1222810-74-3		Potassium Channel
T10566	BMS-191095		Potassium Channel
	BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.		Potassium Channel
T3102	NS-1619		Apoptosis , Potassium Channel
	NS1619 have cardio-protective effects after ischemia-reperfusion injury.		Apoptosis , Potassium Channel